AuraSense's uniquely engineered nanoparticles possess unparalleled biocompatibility and versatility as novel assays within live cells. AuraSense particles exhibit high stability, high binding specificity, and unparalleled transfection efficiency into numerous cell and tissue types. Needing no carriers or transfection agents, they provoke minimal immune response and no known toxicity. As a result, they enable unprecedented interrogation of genetic expression in live cells. These constructs are available as SmartFlareTM detection probes from our commercial partner, EMD Millipore.
AuraSense has also developed nanoparticles that mimic the natural function of HDL ("good" cholesterol). These structures bind cholesterol tightly and have demonstrated activity and minimal toxicity in animal models.
AuraSense's technology originates in the labs of Professors Chad A. Mirkin and C. Shad Thaxton at the Northwestern University International Institute for Nanotechnology. The Company's scientific founders and their developments have been the subject of over 80 international and national awards, 500 publications, and 450 patents.
SmartFlare is a trademark of Merck KGaA
Intracellular Assays in Living Cells